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What is the Entourage Effect?

Cannabis itself contains hundreds of molecules interacting with our minds and bodies. Cannabinoid molecules are unique to the cannabis plant, but other plant-derived molecules such as flavonoids and terpenes also bind to our receptors, influencing our experiences. All of these cannabis-derived molecules work together, potentially enhancing the effects you’re most looking for from your experience. 

Terpenes, for instance, are an essential piece of the cannabis puzzle. They support, if not directly enhance, the therapeutic strength of cannabinoids such as THC and CBD. The relationship between cannabis compounds is known as the entourage, or ensemble, effect.  

The term entourage effect was coined by Israeli researcher Dr. Raphael Mechoulam to explain how a combination of cannabis compounds is more effective than one isolated compound. More recently, the term ensemble effect has been used to describe how phytocannabinoids, terpenes, and other cannabis compounds work together, rather than one cannabinoid taking charge. At the same time, the rest follow, as the word entourage implies.

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